Questions About KEVZARA?

Here are some answers.

KEVZARA (sarilumab) is an injectable prescription medicine called an interleukin-6 (IL-6) receptor blocker. KEVZARA is used to treat adult patients with moderately to severely active rheumatoid arthritis (RA) after at least one other medicine called a disease-modifying antirheumatic drug (DMARD) has been used and did not work well or could not be tolerated.

Do not use KEVZARA if you are allergic to sarilumab or any of the ingredients in KEVZARA. See the end of the Medication Guide for a complete list of ingredients in KEVZARA.

KEVZARA® (sarilumab) can cause serious side effects including:

  • SERIOUS INFECTIONS: KEVZARA is a medicine that affects your immune system. KEVZARA can lower the ability of your immune system to fight infections. Some people have serious infections while using KEVZARA, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections.
    • Before starting KEVZARA, tell your healthcare provider if you:
      • think you have an infection or have symptoms of an infection, with or without a fever, such as sweats or chills, muscle aches, cough, shortness of breath, blood in phlegm, weight loss, warm, red or painful skin or sores on your body, diarrhea or stomach pain, burning when you urinate or urinating more often than normal or feel very tired; or are being treated for an infection, get a lot of infections or have repeated infections
      • have diabetes, HIV, or a weakened immune system
      • have TB, or have been in close contact with someone with TB
      • live or have lived, or have traveled to certain parts of the country (such as the Ohio and Mississippi River valleys and the Southwest) where there is an increased chance of getting certain fungal infections (histoplasmosis, coccidioidomycosis, or blastomycosis)
      • have or have had hepatitis
    • After starting KEVZARA, call your healthcare provider right away if you have any symptoms of an infection.
  • CHANGES IN CERTAIN LABORATORY TEST RESULTS: Your healthcare provider should do blood tests before and after starting KEVZARA to check for low neutrophil (white blood cells that help the body fight off bacterial infections) counts, low platelet (blood cells that help with blood clotting and stop bleeding) counts, and an increase in certain liver function tests. Changes in test results are common with KEVZARA and can be severe. You may also have changes in other laboratory tests, such as your blood cholesterol levels.
  • TEARS (PERFORATION) OF THE STOMACH OR INTESTINES: Some people using KEVZARA get tears in their stomach or intestine. Call your healthcare provider right away if you have fever and stomach (abdominal) pain that does not go away.
  • CANCER: KEVZARA may increase your risk of certain cancers by changing the way your immune system works. Tell your healthcare provider if you have ever had any type of cancer.
  • SERIOUS ALLERGIC REACTIONS: Serious allergic reactions can happen with KEVZARA. Get medical attention right away if you have any of the following signs: shortness of breath or trouble breathing; feeling dizzy or faint; swelling of the lips, tongue, or face; moderate or severe stomach (abdominal) pain or vomiting; or chest pain.

These are not all the side effects of KEVZARA. For the full list of side effects, please see the KEVZARA full Prescribing Information and Medication Guide.

Interleukin-6, or IL-6, is a protein that’s produced by the white cells in your blood. Elevated IL-6 levels are believed to be associated with RA.

See the detailed Instructions for Use that come with your Medication Guide for instructions about the right way to give your KEVZARA injections at home. You can also view our injection training video on this site.

  • KEVZARA is given as an injection under the skin (subcutaneous injection)
  • KEVZARA comes as a single-dose (1 time) prefilled syringe. Your healthcare provider will prescribe the dose that is best for you
  • If your healthcare provider decides that you or a caregiver can give the injections of KEVZARA at home, you or your caregiver should receive training on the right way to inject KEVZARA. Do not try to inject KEVZARA until you have been shown the right way to give the injections by your healthcare provider
  • One injection of KEVZARA should be taken every two weeks
  • If you do miss a dose, call your healthcare provider for instructions

Whether you’ve just been prescribed KEVZARA or have already started taking it, the KevzaraConnect® Copay Card helps eligible, commercially insured patients with their copay costs for KEVZARA.

With the copay card, you may qualify to pay a $0 copay per month.* The maximum copay assistance is $15,000 per calendar year.

See the Save with KEVZARA section to apply for the copay card, or to activate an existing KevzaraConnect Copay Card.

*Subject to annual maximum copay assistance amount. This program is not valid for prescriptions covered by or submitted for reimbursement under Medicaid, Medicare, VA, DOD, Tricare or similar federal or state programs, including any state pharmaceutical assistance program.

To help you get started on KEVZARA, we offer the KevzaraConnect® program. KevzaraConnect offers you 24/7 access to information and services, including around-the-clock Nurse Educator support, special kits that offer product information and lifestyle tips, even a travel bag to help store your KEVZARA supplies when you’re on the go.